A mild, catalyst-free synthesis of 2-aminopyridines.
نویسندگان
چکیده
Alkylation of 2-mercaptopyridine with 1,2-dibromoethane affords a cyclic dihydrothiazolopyridinium salt that can serve as a precursor of 2-aminopyridines. Its reaction with primary or secondary amines, either neat or in DMSO, under mild conditions gives the title compounds.
منابع مشابه
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ورودعنوان ژورنال:
- Tetrahedron
دوره 64 48 شماره
صفحات -
تاریخ انتشار 2008